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Design principles for nuclease-deficient CRISPR-based transcriptional regulators
The engineering of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated proteins continues to expand the toolkit available for genome editing, reprogramming gene regulation, genome visualisation and epigenetic studies of living organisms. In this review, the emerging...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932555/ https://www.ncbi.nlm.nih.gov/pubmed/29726937 http://dx.doi.org/10.1093/femsyr/foy039 |