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Hydrostatic pressure suppresses fibrotic changes via Akt/GSK‐3 signaling in human cardiac fibroblasts

Mechanical stresses play important roles in the process of constructing and modifying heart structure. It has been well established that stretch force acting on cardiac fibroblasts induces fibrosis. However, the effects of compressive force, that is, hydrostatic pressure (HP), have not been well elu...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryo, Umemura, Masanari, Narikawa, Masatoshi, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Kimura, Kazuo, Tamura, Kouichi, Ishikawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932570/
https://www.ncbi.nlm.nih.gov/pubmed/29722156
http://dx.doi.org/10.14814/phy2.13687