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Hydrostatic pressure suppresses fibrotic changes via Akt/GSK‐3 signaling in human cardiac fibroblasts
Mechanical stresses play important roles in the process of constructing and modifying heart structure. It has been well established that stretch force acting on cardiac fibroblasts induces fibrosis. However, the effects of compressive force, that is, hydrostatic pressure (HP), have not been well elu...
Autores principales: | Tanaka, Ryo, Umemura, Masanari, Narikawa, Masatoshi, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Kimura, Kazuo, Tamura, Kouichi, Ishikawa, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932570/ https://www.ncbi.nlm.nih.gov/pubmed/29722156 http://dx.doi.org/10.14814/phy2.13687 |
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