Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers

Throughout their lifetime, cells are subject to extrinsic and intrinsic mutational processes leaving behind characteristic signatures in the genome. DNA mismatch repair (MMR) deficiency leads to hypermutation and is found in different cancer types. Although it is possible to associate mutational sig...

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Detalles Bibliográficos
Autores principales: Meier, Bettina, Volkova, Nadezda V., Hong, Ye, Schofield, Pieta, Campbell, Peter J., Gerstung, Moritz, Gartner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932607/
https://www.ncbi.nlm.nih.gov/pubmed/29636374
http://dx.doi.org/10.1101/gr.226845.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932607/
https://www.ncbi.nlm.nih.gov/pubmed/29636374
http://dx.doi.org/10.1101/gr.226845.117

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