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Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome

Understanding the molecular mechanisms and evolution of the gene regulatory system remains a major challenge in biology. Transcription start sites (TSSs) are especially interesting because they are central to initiating gene expression. Previous studies revealed widespread transcription initiation a...

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Detalles Bibliográficos
Autores principales: Li, Cai, Lenhard, Boris, Luscombe, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932608/
https://www.ncbi.nlm.nih.gov/pubmed/29618487
http://dx.doi.org/10.1101/gr.231449.117