Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer

Genomic rearrangements are common in cancer, with demonstrated links to disease progression and treatment response. These rearrangements can be complex, resulting in fusions of multiple chromosomal fragments and generation of derivative chromosomes. Although methods exist for detecting individual fu...

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Detalles Bibliográficos
Autores principales: Chan, Eva K.F., Cameron, Daniel L., Petersen, Desiree C., Lyons, Ruth J., Baldi, Benedetta F., Papenfuss, Anthony T., Thomas, David M., Hayes, Vanessa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932612/
https://www.ncbi.nlm.nih.gov/pubmed/29618486
http://dx.doi.org/10.1101/gr.227975.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932612/
https://www.ncbi.nlm.nih.gov/pubmed/29618486
http://dx.doi.org/10.1101/gr.227975.117

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