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Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis

BACKGROUND: The majority of estrogen receptor-positive (ERα(+)) breast cancers respond to endocrine therapies. However, resistance to endocrine therapies is common in 30% of cases, which may be due to altered ERα signaling and/or enhanced plasticity of cancer cells leading to breast cancer subtype c...

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Detalles Bibliográficos
Autores principales: Padua, Maria B., Bhat-Nakshatri, Poornima, Anjanappa, Manjushree, Prasad, Mayuri S., Hao, Yangyang, Rao, Xi, Liu, Sheng, Wan, Jun, Liu, Yunlong, McElyea, Kyle, Jacobsen, Max, Sandusky, George, Althouse, Sandra, Perkins, Susan, Nakshatri, Harikrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932758/
https://www.ncbi.nlm.nih.gov/pubmed/29720215
http://dx.doi.org/10.1186/s13058-018-0963-5