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Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis
BACKGROUND: The majority of estrogen receptor-positive (ERα(+)) breast cancers respond to endocrine therapies. However, resistance to endocrine therapies is common in 30% of cases, which may be due to altered ERα signaling and/or enhanced plasticity of cancer cells leading to breast cancer subtype c...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932758/ https://www.ncbi.nlm.nih.gov/pubmed/29720215 http://dx.doi.org/10.1186/s13058-018-0963-5 |