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Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease
BACKGROUND: Multiple risk factors contribute to the progression of Parkinson’s disease, including oxidative stress and neuroinflammation. Epidemiological studies have revealed a link between higher urate level and a lower risk of developing PD. However, the mechanistic basis for this association rem...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932803/ https://www.ncbi.nlm.nih.gov/pubmed/29720230 http://dx.doi.org/10.1186/s12974-018-1175-8 |