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Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease

BACKGROUND: Multiple risk factors contribute to the progression of Parkinson’s disease, including oxidative stress and neuroinflammation. Epidemiological studies have revealed a link between higher urate level and a lower risk of developing PD. However, the mechanistic basis for this association rem...

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Detalles Bibliográficos
Autores principales:	Bao, Li-Hui, Zhang, Ya-Nan, Zhang, Jian-Nan, Gu, Li, Yang, Hui-Min, Huang, Yi-Ying, Xia, Ning, Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932803/ https://www.ncbi.nlm.nih.gov/pubmed/29720230 http://dx.doi.org/10.1186/s12974-018-1175-8

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