PM2.5 exposure aggravates oligomeric amyloid beta-induced neuronal injury and promotes NLRP3 inflammasome activation in an in vitro model of Alzheimer’s disease

BACKGROUND: Numerous studies suggested that PM2.5 exposure was associated with increased risk of Alzheimer’s disease (AD). But the precise mechanisms by which PM2.5 contributed to AD pathogenesis have not been clarified. METHODS: In the presence or absence of neurons, oligomeric amyloid beta (oAβ)-p...

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Detalles Bibliográficos
Autores principales: Wang, Bian-Rong, Shi, Jian-Quan, Ge, Nian-Nian, Ou, Zhou, Tian, You-Yong, Jiang, Teng, Zhou, Jun-Shan, Xu, Jun, Zhang, Ying-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932821/
https://www.ncbi.nlm.nih.gov/pubmed/29720213
http://dx.doi.org/10.1186/s12974-018-1178-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932821/
https://www.ncbi.nlm.nih.gov/pubmed/29720213
http://dx.doi.org/10.1186/s12974-018-1178-5

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