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VISTA expression associated with CD8 confers a favorable immune microenvironment and better overall survival in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) often arises in the setting of chronic inflammation with multiple inhibitory immune signals. V-domain Ig suppressor of T cell activation (VISTA) is identified as a novel negative checkpoint regulator. This study sought to determine the expression and progno...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Pang, Hua-Jin, Zhao, Wei, Li, Yu-Fa, Yan, Li-Xu, Dong, Zhong-Yi, He, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932869/
https://www.ncbi.nlm.nih.gov/pubmed/29720116
http://dx.doi.org/10.1186/s12885-018-4435-1