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Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis

BACKGROUND: ADAMTS aggrecanases play a major role in cartilage degeneration during degenerative and inflammatory arthritis. The cartilage-specific secreted protein Upper zone of growth plate and cartilage matrix associated protein (Ucma) has been shown to block ADAMTS-triggered aggrecanolysis in exp...

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Detalles Bibliográficos
Autores principales: Seuffert, Fritz, Weidner, Daniela, Baum, Wolfgang, Schett, Georg, Stock, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932879/
https://www.ncbi.nlm.nih.gov/pubmed/29720262
http://dx.doi.org/10.1186/s13075-018-1583-2