The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://www.ncbi.nlm.nih.gov/pubmed/29560976
http://dx.doi.org/10.1039/c7dt04537a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://www.ncbi.nlm.nih.gov/pubmed/29560976
http://dx.doi.org/10.1039/c7dt04537a

Ejemplares similares