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DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress

DUOX1 is an H(2)O(2)-generating enzyme related to a wide range of biological features, such as hormone synthesis, host defense, cellular proliferation, and fertilization. DUOX1 is frequently downregulated in lung and liver cancers, suggesting a tumor suppressor role for this enzyme. Here, we show th...

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Detalles Bibliográficos
Autores principales: Fortunato, Rodrigo S., Gomes, Luciana R., Munford, Veridiana, Pessoa, Carolina Fittipaldi, Quinet, Annabel, Hecht, Fabio, Kajitani, Gustavo S., Milito, Cristiane Bedran, Carvalho, Denise P., Menck, Carlos Frederico Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933011/
https://www.ncbi.nlm.nih.gov/pubmed/29849884
http://dx.doi.org/10.1155/2018/3570526