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DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress
DUOX1 is an H(2)O(2)-generating enzyme related to a wide range of biological features, such as hormone synthesis, host defense, cellular proliferation, and fertilization. DUOX1 is frequently downregulated in lung and liver cancers, suggesting a tumor suppressor role for this enzyme. Here, we show th...
Autores principales: | Fortunato, Rodrigo S., Gomes, Luciana R., Munford, Veridiana, Pessoa, Carolina Fittipaldi, Quinet, Annabel, Hecht, Fabio, Kajitani, Gustavo S., Milito, Cristiane Bedran, Carvalho, Denise P., Menck, Carlos Frederico Martins |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933011/ https://www.ncbi.nlm.nih.gov/pubmed/29849884 http://dx.doi.org/10.1155/2018/3570526 |
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