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Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats

Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics. Whether diabetics with CVSP also benefit from this drug, however, is unknown. We evaluate...

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Detalles Bibliográficos
Autores principales: Crespo, Maria J., Roman, Marie, Matias, Jonathan, Morales, Myrna, Torres, Hector, Quidgley, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933070/
https://www.ncbi.nlm.nih.gov/pubmed/29849627
http://dx.doi.org/10.1155/2018/9790303