Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7

BACKGROUND: Adamantane-based compounds have been identified to interfere with the ion-channel activity of viroporins and thereby inhibit viral infection. To better understand the difference in the inhibition mechanism of viroporins, we synthesized symmetric dimeric adamantane analogs of various alky...

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Detalles Bibliográficos
Autores principales: Mandour, Yasmine M, Breitinger, Ulrike, Ma, Chunlong, Wang, Jun, Boeckler, Frank M, Breitinger, Hans-Georg, Zlotos, Darius P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933338/
https://www.ncbi.nlm.nih.gov/pubmed/29750015
http://dx.doi.org/10.2147/DDDT.S157104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933338/
https://www.ncbi.nlm.nih.gov/pubmed/29750015
http://dx.doi.org/10.2147/DDDT.S157104

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