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Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium(iii) complexes

Cancer cell metabolism is reprogrammed to sustain the high metabolic demands of cell proliferation. Recently, emerging studies have shown that mitochondrial metabolism is a potential target for cancer therapy. Herein, four mitochondria-targeted phosphorescent cyclometalated iridium(iii) complexes ha...

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Detalles Bibliográficos
Autores principales: Cao, Jian-Jun, Tan, Cai-Ping, Chen, Mu-He, Wu, Na, Yao, De-Yang, Liu, Xing-Guo, Ji, Liang-Nian, Mao, Zong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933427/
https://www.ncbi.nlm.nih.gov/pubmed/29780446
http://dx.doi.org/10.1039/c6sc02901a