Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster

The insulin family of growth factors plays an important role in development and function of the nervous system. Reduced insulin and insulin-growth-factor signaling (IIS), however, can improve symptoms of neurodegenerative diseases in laboratory model organisms and protect against age-associated decl...

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Detalles Bibliográficos
Autores principales: Augustin, Hrvoje, McGourty, Kieran, Allen, Marcus J., Adcott, Jennifer, Wong, Chi Tung, Boucrot, Emmanuel, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933513/
https://www.ncbi.nlm.nih.gov/pubmed/29579685
http://dx.doi.org/10.1016/j.neurobiolaging.2018.02.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933513/
https://www.ncbi.nlm.nih.gov/pubmed/29579685
http://dx.doi.org/10.1016/j.neurobiolaging.2018.02.027

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