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Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles

The Adeno-associated virus (AAV) gene delivery system is ushering in a new and exciting era in the United States; following the first approved gene therapy (Glybera) in Europe, the FDA has approved a second therapy, Luxturna [1]. However, challenges to this system remain. In viral gene therapy, the...

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Detalles Bibliográficos
Autores principales: Smith, J. Kennon, Agbandje-McKenna, Mavis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933702/
https://www.ncbi.nlm.nih.gov/pubmed/29723270
http://dx.doi.org/10.1371/journal.ppat.1006929