Fc engineering of anti-Nectin-2 antibody improved thrombocytopenic adverse event in monkey

Nectin-2 is a transmembrane glycoprotein which is involved in the process of Ca(2+)-independent cell-cell adhesion. In our previous study, we have demonstrated that Nectin-2 is over-expressed in breast and ovarian cancer tissues by using gene expression analysis and immunohistochemistry. Furthermore...

Descripción completa

Detalles Bibliográficos
Autores principales: Oshima, Tsutomu, Miyashita, Hideaki, Ishimura, Yoshimasa, Ito, Yuki, Tanaka, Yoko, Hori, Akira, Kokubo, Toshio, Kurokawa, Tomofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933732/
https://www.ncbi.nlm.nih.gov/pubmed/29723247
http://dx.doi.org/10.1371/journal.pone.0196422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933732/
https://www.ncbi.nlm.nih.gov/pubmed/29723247
http://dx.doi.org/10.1371/journal.pone.0196422

Ejemplares similares