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Fc engineering of anti-Nectin-2 antibody improved thrombocytopenic adverse event in monkey
Nectin-2 is a transmembrane glycoprotein which is involved in the process of Ca(2+)-independent cell-cell adhesion. In our previous study, we have demonstrated that Nectin-2 is over-expressed in breast and ovarian cancer tissues by using gene expression analysis and immunohistochemistry. Furthermore...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933732/ https://www.ncbi.nlm.nih.gov/pubmed/29723247 http://dx.doi.org/10.1371/journal.pone.0196422 |