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Probing the role of PPARγ in the regulation of late-onset Alzheimer’s disease-associated genes

Peroxisome proliferator-activated receptor-γ (PPARγ), is a transcription factor that governs pathways, such as lipid metabolism and immune response, that have been implicated in the etiology of LOAD. Previously, we established HepG2-derived cell-lines with stable knockdown of PPARγ gene, and showed...

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Detalles Bibliográficos
Autores principales: Barrera, Julio, Subramanian, Shobana, Chiba-Falek, Ornit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933777/
https://www.ncbi.nlm.nih.gov/pubmed/29723294
http://dx.doi.org/10.1371/journal.pone.0196943