Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis

Transforming growth factor-β1 (TGF-β1) is a major mediator of peritoneal fibrosis and reportedly affects expression of the H3K4 methyltransferase, SET7/9. SET7/9-induced H3K4 mono-methylation (H3K4me1) critically activates transcription of fibrosis-related genes. In this study, we examined the effec...

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Detalles Bibliográficos
Autores principales: Tamura, Ryo, Doi, Shigehiro, Nakashima, Ayumu, Sasaki, Kensuke, Maeda, Kazuya, Ueno, Toshinori, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933785/
https://www.ncbi.nlm.nih.gov/pubmed/29723250
http://dx.doi.org/10.1371/journal.pone.0196844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933785/
https://www.ncbi.nlm.nih.gov/pubmed/29723250
http://dx.doi.org/10.1371/journal.pone.0196844

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