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Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis
Transforming growth factor-β1 (TGF-β1) is a major mediator of peritoneal fibrosis and reportedly affects expression of the H3K4 methyltransferase, SET7/9. SET7/9-induced H3K4 mono-methylation (H3K4me1) critically activates transcription of fibrosis-related genes. In this study, we examined the effec...
Autores principales: | Tamura, Ryo, Doi, Shigehiro, Nakashima, Ayumu, Sasaki, Kensuke, Maeda, Kazuya, Ueno, Toshinori, Masaki, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933785/ https://www.ncbi.nlm.nih.gov/pubmed/29723250 http://dx.doi.org/10.1371/journal.pone.0196844 |
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