Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

RNA interference (RNAi) is a major powerful platform for gene perturbations, but is restricted by off-target mechanisms. Communication between RNAs, small RNAs, and RNA-binding proteins (RBPs) is a pervasive feature of cellular RNA networks. We present a new crosstalk scenario, designated as “crosst...

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Detalles Bibliográficos
Autores principales: Suzuki, Hiroshi I., Spengler, Ryan M., Grigelioniene, Giedre, Kobayashi, Tatsuya, Sharp, Phillip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934319/
https://www.ncbi.nlm.nih.gov/pubmed/29662165
http://dx.doi.org/10.1038/s41588-018-0104-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934319/
https://www.ncbi.nlm.nih.gov/pubmed/29662165
http://dx.doi.org/10.1038/s41588-018-0104-1

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