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Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics
RNA interference (RNAi) is a major powerful platform for gene perturbations, but is restricted by off-target mechanisms. Communication between RNAs, small RNAs, and RNA-binding proteins (RBPs) is a pervasive feature of cellular RNA networks. We present a new crosstalk scenario, designated as “crosst...
Autores principales: | Suzuki, Hiroshi I., Spengler, Ryan M., Grigelioniene, Giedre, Kobayashi, Tatsuya, Sharp, Phillip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934319/ https://www.ncbi.nlm.nih.gov/pubmed/29662165 http://dx.doi.org/10.1038/s41588-018-0104-1 |
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