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Gene-based analysis of genes related to neurotrophic pathway suggests association of BDNF and VEGFA with antidepressant treatment-response in depressed patients

It is well established that brain-derived neurotrophic factor (BDNF) signaling pathway plays a key role in the pathophysiology of major depressive disorder (MDD) and in therapeutic mechanisms of antidepressants. We aim to identify genetic vairiants related to MDD susceptibility and antidepressant th...

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Detalles Bibliográficos
Autores principales: Kao, Chung-Feng, Liu, Yu-Li, Yu, Younger W.-Y., Yang, Albert C., Lin, Eugene, Kuo, Po-Hsiu, Tsai, Shih-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934385/
https://www.ncbi.nlm.nih.gov/pubmed/29725086
http://dx.doi.org/10.1038/s41598-018-25529-y