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Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy

Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear. Transforming Growth Factor- β1 (TGF-β), a key player in the pathogenesis of DN, regulates expression of var...

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Detalles Bibliográficos
Autores principales: Deshpande, Supriya, Abdollahi, Maryam, Wang, Mei, Lanting, Linda, Kato, Mitsuo, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934412/
https://www.ncbi.nlm.nih.gov/pubmed/29725042
http://dx.doi.org/10.1038/s41598-018-25295-x