RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes

The potent proinflammatory cytokine interleukin (IL)-1 triggers gene expression through the NF-κB signaling pathway. Here, we investigated the cofactor requirements of strongly regulated IL-1 target genes whose expression is impaired in p65 NF-κB-deficient murine embryonic fibroblasts. By two indepe...

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Detalles Bibliográficos
Autores principales: Meier-Soelch, Johanna, Jurida, Liane, Weber, Axel, Newel, Doris, Kim, Johnny, Braun, Thomas, Schmitz, M. Lienhard, Kracht, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934416/
https://www.ncbi.nlm.nih.gov/pubmed/29755455
http://dx.doi.org/10.3389/fimmu.2018.00775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934416/
https://www.ncbi.nlm.nih.gov/pubmed/29755455
http://dx.doi.org/10.3389/fimmu.2018.00775

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