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Computational Protein Phenotype Characterization of IL10RA Mutations Causative to Early Onset Inflammatory Bowel Disease (IBD)

The deleterious amino acid substitution mutations in IL-10 receptor alpha gene are most frequently reported in several autoimmune diseases including early onset-inflammatory bowel disease (IBD). Despite the important role of IL-10 RA in maintaining immune homeostasis, the specific structural and fun...

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Detalles Bibliográficos
Autores principales: Al-Abbasi, Fahad A., Mohammed, Kaleemuddin, Sadath, Saida, Banaganapalli, Babajan, Nasser, Khalidah, Shaik, Noor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934427/
https://www.ncbi.nlm.nih.gov/pubmed/29755507
http://dx.doi.org/10.3389/fgene.2018.00146