Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology

A previous study of exome-sequenced schizophrenia cases and controls reported an excess of singleton, gene-disruptive variants among cases, concentrated in particular gene sets. The dataset included a number of subjects with a substantial Finnish contribution to ancestry. We have reanalysed the same...

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Detalles Bibliográficos
Autores principales: Curtis, David, Coelewij, Leda, Liu, Shou-Hwa, Humphrey, Jack, Mott, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934462/
https://www.ncbi.nlm.nih.gov/pubmed/29564678
http://dx.doi.org/10.1007/s10519-018-9893-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934462/
https://www.ncbi.nlm.nih.gov/pubmed/29564678
http://dx.doi.org/10.1007/s10519-018-9893-3

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