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Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology
A previous study of exome-sequenced schizophrenia cases and controls reported an excess of singleton, gene-disruptive variants among cases, concentrated in particular gene sets. The dataset included a number of subjects with a substantial Finnish contribution to ancestry. We have reanalysed the same...
Autores principales: | Curtis, David, Coelewij, Leda, Liu, Shou-Hwa, Humphrey, Jack, Mott, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934462/ https://www.ncbi.nlm.nih.gov/pubmed/29564678 http://dx.doi.org/10.1007/s10519-018-9893-3 |
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