Cargando…

(Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis

Parkinson’s disease (PD) is an age-related neurodegenerative disease associated with the misfolding and aggregation of alpha-synuclein (aSyn). The molecular underpinnings of PD are still obscure, but nutrition may play an important role in the prevention, onset, and disease progression. Dietary (pol...

Descripción completa

Detalles Bibliográficos
Autores principales: Macedo, Diana, Jardim, Carolina, Figueira, Inês, Almeida, A. Filipa, McDougall, Gordon J., Stewart, Derek, Yuste, Jose E., Tomás-Barberán, Francisco A., Tenreiro, Sandra, Outeiro, Tiago F., Santos, Cláudia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934470/
https://www.ncbi.nlm.nih.gov/pubmed/29725038
http://dx.doi.org/10.1038/s41598-018-25118-z