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(Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis
Parkinson’s disease (PD) is an age-related neurodegenerative disease associated with the misfolding and aggregation of alpha-synuclein (aSyn). The molecular underpinnings of PD are still obscure, but nutrition may play an important role in the prevention, onset, and disease progression. Dietary (pol...
Autores principales: | Macedo, Diana, Jardim, Carolina, Figueira, Inês, Almeida, A. Filipa, McDougall, Gordon J., Stewart, Derek, Yuste, Jose E., Tomás-Barberán, Francisco A., Tenreiro, Sandra, Outeiro, Tiago F., Santos, Cláudia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934470/ https://www.ncbi.nlm.nih.gov/pubmed/29725038 http://dx.doi.org/10.1038/s41598-018-25118-z |
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