Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity

Radiation therapy is a source of tumor antigen release that has the potential to serve as an endogenous tumor vaccination event. In preclinical models radiation therapy synergizes with checkpoint inhibitors to cure tumors via CD8 T cell responses. To evaluate the immune response initiated by radiati...

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Detalles Bibliográficos
Autores principales: Crittenden, Marka R., Zebertavage, Lauren, Kramer, Gwen, Bambina, Shelly, Friedman, David, Troesch, Victoria, Blair, Tiffany, Baird, Jason R., Alice, Alejandro, Gough, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934473/
https://www.ncbi.nlm.nih.gov/pubmed/29725089
http://dx.doi.org/10.1038/s41598-018-25482-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934473/
https://www.ncbi.nlm.nih.gov/pubmed/29725089
http://dx.doi.org/10.1038/s41598-018-25482-w

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