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Genetic Ablation of EWS RNA Binding Protein 1 (EWSR1) Leads to Neuroanatomical Changes and Motor Dysfunction in Mice

A recent study reveals that missense mutations of EWSR1 are associated with neurodegenerative disorders such as amyotrophic lateral sclerosis, but the function of wild-type (WT) EWSR1 in the central nervous system (CNS) is not known yet. Herein, we investigated the neuroanatomical and motor function...

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Detalles Bibliográficos
Autores principales: Yoon, Yeojun, Park, Hasang, Kim, Sangyeon, Nguyen, Phuong T., Hyeon, Seung Jae, Chung, Sooyoung, Im, Hyeonjoo, Lee, Junghee, Lee, Sean Bong, Ryu, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934541/
https://www.ncbi.nlm.nih.gov/pubmed/29731676
http://dx.doi.org/10.5607/en.2018.27.2.103