Translation initiation of alphavirus mRNA reveals new insights into the topology of the 48S initiation complex

The topology and dynamics of the scanning ribosomal 43S pre-initiation complex (PIC) bound to mRNA and initiation factors (eIFs) are probably the least understood aspects of translation initiation in eukaryotes. Recently, we described a trapping mechanism in alphavirus that stalls the PIC during sca...

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Detalles Bibliográficos
Autores principales: Toribio, René, Díaz-López, Irene, Boskovic, Jasminka, Ventoso, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934618/
https://www.ncbi.nlm.nih.gov/pubmed/29415133
http://dx.doi.org/10.1093/nar/gky071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934618/
https://www.ncbi.nlm.nih.gov/pubmed/29415133
http://dx.doi.org/10.1093/nar/gky071

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