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DNA lesions proximity modulates damage tolerance pathways in Escherichia coli

The genome of all organisms is constantly threatened by numerous agents that cause DNA damage. When the replication fork encounters an unrepaired DNA lesion, two DNA damage tolerance pathways are possible: error-prone translesion synthesis (TLS) that requires specialized DNA polymerases, and error-f...

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Detalles Bibliográficos
Autores principales: Chrabaszcz, Élodie, Laureti, Luisa, Pagès, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934622/
https://www.ncbi.nlm.nih.gov/pubmed/29529312
http://dx.doi.org/10.1093/nar/gky135