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In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality
Aptamer-based sensors offer a powerful tool for molecular detection, but the practical implementation of these biosensors is hindered by costly and laborious sequence engineering and chemical modification procedures. We report a simple strategy for directly isolating signal-reporting aptamers in vit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934630/ https://www.ncbi.nlm.nih.gov/pubmed/29361056 http://dx.doi.org/10.1093/nar/gky026 |