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Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation
Precursor message RNA (pre-mRNA) splicing is executed by the spliceosome, a large ribonucleoprotein (RNP) machinery that is comparable to the ribosome. Driven by the rapid progress of cryo-electron microscopy (cryo-EM) technology, high resolution structures of the spliceosome in its different splici...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934631/ https://www.ncbi.nlm.nih.gov/pubmed/29635373 http://dx.doi.org/10.1093/nar/gky242 |