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LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS

Oncogene-induced senescence (OIS), provoked in response to oncogenic activation, is considered an important tumor suppressor mechanism. Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nt without a protein-coding capacity. Functional studies showed that deregulated lncRNA expression pr...

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Detalles Bibliográficos
Autores principales: Li, Li, van Breugel, Pieter C, Loayza-Puch, Fabricio, Ugalde, Alejandro Pineiro, Korkmaz, Gozde, Messika-Gold, Naama, Han, Ruiqi, Lopes, Rui, Barbera, Eric P, Teunissen, Hans, de Wit, Elzo, Soares, Ricardo J, Nielsen, Boye S, Holmstrøm, Kim, Martínez-Herrera, Dannys J, Huarte, Maite, Louloupi, Annita, Drost, Jarno, Elkon, Ran, Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934637/
https://www.ncbi.nlm.nih.gov/pubmed/29481642
http://dx.doi.org/10.1093/nar/gky087