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Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering
Transposable elements are efficient DNA carriers and thus important tools for transgenesis and insertional mutagenesis. However, their poor target sequence specificity constitutes an important limitation for site-directed applications. The insertion sequence IS608 from Helicobacter pylori recognizes...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934647/ https://www.ncbi.nlm.nih.gov/pubmed/29635476 http://dx.doi.org/10.1093/nar/gky235 |