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Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state

Formation of RAD51 filaments on single-stranded DNA is an essential event during homologous recombination, which is required for homology search, strand exchange and protection of replication forks. Formation of nucleoprotein filaments (NF) is required for development and genomic stability, and its...

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Detalles Bibliográficos
Autores principales: Špírek, Mário, Mlčoušková, Jarmila, Beláň, Ondrej, Gyimesi, Máté, Harami, Gábor M, Molnár, Eszter, Novacek, Jiri, Kovács, Mihály, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934667/
https://www.ncbi.nlm.nih.gov/pubmed/29481689
http://dx.doi.org/10.1093/nar/gky111