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Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
Formation of RAD51 filaments on single-stranded DNA is an essential event during homologous recombination, which is required for homology search, strand exchange and protection of replication forks. Formation of nucleoprotein filaments (NF) is required for development and genomic stability, and its...
Autores principales: | Špírek, Mário, Mlčoušková, Jarmila, Beláň, Ondrej, Gyimesi, Máté, Harami, Gábor M, Molnár, Eszter, Novacek, Jiri, Kovács, Mihály, Krejci, Lumir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934667/ https://www.ncbi.nlm.nih.gov/pubmed/29481689 http://dx.doi.org/10.1093/nar/gky111 |
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