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Cytotoxic and mutagenic properties of alkyl phosphotriester lesions in Escherichia coli cells

Exposure to many endogenous and exogenous agents can give rise to DNA alkylation, which constitutes a major type of DNA damage. Among the DNA alkylation products, alkyl phosphotriesters have relatively high frequencies of occurrence and are resistant to repair in mammalian tissues. However, little i...

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Detalles Bibliográficos
Autores principales: Wu, Jiabin, Wang, Pengcheng, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934668/
https://www.ncbi.nlm.nih.gov/pubmed/29514270
http://dx.doi.org/10.1093/nar/gky140