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Cytotoxic and mutagenic properties of alkyl phosphotriester lesions in Escherichia coli cells
Exposure to many endogenous and exogenous agents can give rise to DNA alkylation, which constitutes a major type of DNA damage. Among the DNA alkylation products, alkyl phosphotriesters have relatively high frequencies of occurrence and are resistant to repair in mammalian tissues. However, little i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934668/ https://www.ncbi.nlm.nih.gov/pubmed/29514270 http://dx.doi.org/10.1093/nar/gky140 |