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High-resolution 3D models of Caulobacter crescentus chromosome reveal genome structural variability and organization

High-resolution three-dimensional models of Caulobacter crescentus nucleoid structures were generated via a multi-scale modeling protocol. Models were built as a plectonemically supercoiled circular DNA and by incorporating chromosome conformation capture based data to generate an ensemble of base p...

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Detalles Bibliográficos
Autores principales: Yildirim, Asli, Feig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934669/
https://www.ncbi.nlm.nih.gov/pubmed/29529244
http://dx.doi.org/10.1093/nar/gky141