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Modular discovery of monomeric and dimeric transcription factor binding motifs for large data sets

In some dimeric cases of transcription factor (TF) binding, the specificity of dimeric motifs has been observed to differ notably from what would be expected were the two factors to bind to DNA independently of each other. Current motif discovery methods are unable to learn monomeric and dimeric mot...

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Detalles Bibliográficos
Autores principales: Toivonen, Jarkko, Kivioja, Teemu, Jolma, Arttu, Yin, Yimeng, Taipale, Jussi, Ukkonen, Esko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934673/
https://www.ncbi.nlm.nih.gov/pubmed/29385521
http://dx.doi.org/10.1093/nar/gky027