N (6)-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential

Previous studies have revealed the critical roles of N(6)-methyladenosine (m(6)A) modification of mRNA in embryonic stem cells (ESCs), but the biological function of m(6)A in large intergenic noncoding RNA (lincRNA) is unknown. Here, we showed that the internal m(6)A modification of linc1281 mediate...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Dandan, Qiao, Jing, Wang, Guiying, Lan, Yuanyuan, Li, Guoping, Guo, Xudong, Xi, Jiajie, Ye, Dan, Zhu, Songcheng, Chen, Wen, Jia, Wenwen, Leng, Ye, Wan, Xiaoping, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934679/
https://www.ncbi.nlm.nih.gov/pubmed/29529255
http://dx.doi.org/10.1093/nar/gky130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934679/
https://www.ncbi.nlm.nih.gov/pubmed/29529255
http://dx.doi.org/10.1093/nar/gky130

Ejemplares similares